Antoine Griezmann fired them in front from the penalty spot early on before Angel Di Maria’s brilliant long-range effort drew La Albiceleste level.
Argentina then took the lead when Gabriel Mercado deflected in Lionel Messi’s effort, but Les Bleus stormed back in front via Benjamin Pavard’s contender for goal of the tournament and Mbappe’s driven first.
The Paris Saint-Germain star then finished a fine team move to make it 4-2, with Sergio Aguero’s late header proving in vain.
Uruguay have reached the World Cup’s knockout phase as the only nation yet to concede a goal, though that record is likely to come under serious threat when they face Ronaldo in Sochi.
Only Harry Kane has scored more in Russia than the 33-year-old, whose form has been so good that Donald Trump even asked his Portuguese counterpart if Ronaldo would ever run for president during a White House visit this week.
Ronaldo is likely to come up against arguably the strongest centre-back pairing at the tournament in Atletico Madrid duo Diego Godin and Jose Maria Gimenez.
However, Tabarez insists neither man is capable of handling Ronaldo on their own.
“I believe that Cristiano Ronaldo is one of the best strikers in the world,” the Uruguay coach told a pre-match press conference.
“What Ronaldo has on top of all of these qualities is that he’s the leader of that team. That is an additional factor.
“There’s not a single player who can contain him. Not just Godin. We will have to work collectively in order to try and limit the effect that he can have.”
How Godin and Gimenez fare against Ronaldo is one of the intriguing subplots surrounding this fixture, though both sides’ defensive records have some fearing a dull contest.
After their 3-3 draw with Spain in their opening World Cup game, Portugal have not conceded a goal from open play and they shipped just one in their four knockout games at Euro 2016.
Asked whether Saturday’s contest with Uruguay could be “boring”, Portugal boss Fernando Santos told a press conference: “No, I don’t think so.
“I think it’s going to be a great match. Two teams are going to try and win – each team using their weapons.
“I hope it’s going to be a great clash between these two teams because it’s very different from the group stages – either you win or you lose. Portugal wants to win.”
Tabaraz, meanwhile, is not concerned with the level of entertainment.
“I don’t know what the match will be like,” he said. “Maybe you are worried that it might start being boring; we don’t even think about that. We’re there to win.”
Despite the high-stakes nature of the fixture, Tabaraz has reported his camp is a relaxed one having been impressed by what he has seen in Uruguay’s victories over Egypt, Saudi Arabia and Russia.
“The last three matches we’ve started showing what we’re trying to achieve and it’s become apparent on the pitch,” he said.
“I believe that we are closer than ever to achieving our real objectives. We want to achieve this at the World Cup.
“Above and beyond the importance of the match – what it means to win or lose – I think we have a certain calmness and serenity in terms of facing it.”
Gareth Southgate could not have been more impressed by captain Harry Kane‘s response to seeing his Golden Boot tilt put on hold, praising the sharpshooter’s collective focus ahead of the World Cup knockout phase.
With progress to the last-16 assured with a match to spare, the Three Lions boss used Thursday’s Group G clash against Belgium as a chance to give squad players a run out and rest star men.
Speculation was rife as to who would be dropped in Kaliningrad, and skipper Kane was reduced to a watching brief in the 1-0 loss despite scoring five goals across the matches against Tunisia and Panama.
“I felt the need to sit with him, but he was brilliant, absolutely brilliant,” Southgate said of the striker.
“He totally understood 100 per cent team first.
“He said ‘look, I know everyone says I want the Golden Boot – of course it’s something I want to do – but the main thing is getting the team through the first knockout’.
“He was excellent on that, showed real leadership and understanding of the big picture.”
Kane will come straight back into the side for what Southgate called England’s “biggest match in a decade”.
Should they lose to Colombia, the boss is sure to come under pressure for his eight changes against Belgium as well as his reluctance to bring on his skipper and chase the draw that would have seen them top Group G and face Japan.
Asked if he had put himself under pressure by making so many alterations in Kaliningrad, Southgate said: “Well, maybe I have, maybe I haven’t. That is the least of my concerns.
“The most important thing for me is the players are in the best physical condition for the game.
“I don’t think mentally we lose anything because they know we’ve made changes and they know Belgium weren’t their full team as well.
“So, we’re in to big matches where margins will be fine and judgement on me will be extremely harsh. That’s why we’re here.
“We want to be in those games. I wasn’t so comfortable with the love-in (before the game), to be honest, so nice that there’s a little bit of an edge back.”
Southgate is hoping to lead England to their first knockout win since 2006 in Moscow, where he believes his side will rise to the “fantastic challenge” posed by Colombia and reach the quarter-finals.
Success at the Spartak Stadium would highlight the progress in the two years since England’s last major tournament ended with a humiliating Euro 2016 exit to Iceland.
“Many different reasons,” Southgate said of England’s knockout struggles. “But you’re playing against the best players in the world.
“We’ve at times had a squad with real top players and at times we’ve had a squad with not such outstanding players who’ve been in those knockout situations.
After a big session in the gym, the #ThreeLions will be back on the pitch this morning.
— England (@England) June 30, 2018
“There’ve been many different reasons for not getting over the line. Some disciplinary, some have been penalty shoot outs.
“But more often than not we have not been able to win those matches in normal time or in extra time.
“So loads of different reasons, but the main one being the level of the opposition, playing against the very best.
They pose you different technical and tactical challenges as we had (against Belgium).”
But star-studded Colombia are sure to prove a far tougher test than Belgium’s back-ups in Moscow.
“It’s exciting,” Southgate said of the clash. “We’ve got the chance to be the team that changes that.
“It’s one of the reasons why we’ve done what we did (against Belgium), to give ourselves the best possible opportunity of doing that.
“For me, it’s going to be a brilliant game to be involved in.
“It looked like Colombia had 30,000-40,000 fans in the stadium. I went to two of their games in Brazil (four years ago) – they were incredible occasions.
“They have some top players, some top attacking players in particular.
“But we also have some really good players who are full of belief and looking forward to this challenge.”