Jordan Spieth is seeking to become just the sixth man in history to complete a career grand slam by winning the US PGA Championship at Quail Hollow.
Here, Press Association Sport looks at some former greats who fell one leg short of winning all four majors.
MISSING MAJOR: MASTERS
Trevino won six majors during his career, winning his third leg of the career grand slam with victory in the 1974 PGA Championship by a margin of just one stroke over fierce rival Jack Nicklaus.
‘The Merry Mex’ did not fare well at Augusta National and even turned down his invitation to play on three occasions, with his best finish a tie for 10th in 1975 and 1985.
MISSING MAJOR: US OPEN
Mickelson won his first of three Masters titles in 2004 and the US PGA the following year, but it was not until 2013 that he won the Open Championship at Muirfield.
By that point he had already finished runner-up in the US Open a record six times, most famously making a double bogey on the 72nd hole at Winged Foot in 2006 when he needed a par to win.
MISSING MAJOR: PGA CHAMPIONSHIP
Watson enjoyed great success at The Open, lifting the Claret Jug five times between 1975 and 1983.
The American won eight major championships in total, including two Masters victories and his sole triumph at the US Open in 1982.
Watson’s best performance in the US PGA Championship came long before he was aiming to complete the set, when he and Jerry Pate were beaten in a play-off by John Mahaffey.
MISSING MAJOR: PGA CHAMPIONSHIP
Palmer won seven major championships throughout his career, including four Masters titles.
His sole triumph at the US Open came in 1960, before winning back-to-back Open Championship’s in 1961 and 1962.
Palmer, who died in September 2016 at the age of 87, finished runner-up three times in the US PGA, finishing just a shot behind Julius Boros in 1968.
Who will reign at Quail Hollow this weekend?
Second-ranked Spieth won last month’s British Open for his third career major title after the 2015 Masters and US Open and at 24 could become the youngest player to complete a Career Grand Slam by winning the PGA title this week.
Seeking his fourth title of the year after US PGA Tour titles at Pebble Beach in February and the Travelers Championship in June.
A winner of US PGA Tour titles at Quail Hollow in 2010 and 2015 and only lost in 2012 in a playoff.
He broke his own course record with a 61 in the third round two years ago.
He also owns two PGA Championship titles from 2012 and 2014 but hasn’t won a major since lifting the Wanamaker Trophy three years ago.
Wet and soggy conditions are expected all week, which should play to his strengths as a long and accurate driver. His putter will be crucial. And it’s his first major since he split with long-time caddie J.P. Fitzgerald, with best pal Harry Diamond being his bagman this week.
World number one says he’s almost back to the level where he was before injuring his back on the eve of the Masters.
He had won at Riviera and taken the World Golf Championships Mexico and Match-Play titles to top the rankings and become a clear favorite.
His long driving should keep him in the hunt despite expected wet conditions.
Won last week’s World Golf Championships Bridgestone Invitational to serve notice he has the game for a breakthrough major triumph at Quail Hollow, what would be the first by any Japanese man and only the second for any Asian man after South Korean Yang Yong-Eun at the 2009 PGA at Hazeltine.
Was US Open co-runner-up in June to Brooks Koepka at Erin Hills. Also won in February at Phoenix Open.
The 39-year-old American enjoyed his best major finish with a runner-up effort behind Spieth at the British Open.
Kuchar, who also shared fourth this year at the Masters, has nine top-10s in majors without a victory.
Could a major breakthrough be on tap at the PGA? The only PGA Championship winner since 2008 who wasn’t a first-time major winner was McIlroy in 2012 and 2014.
Hideki Matsuyama fired a course record-equalling nine-under par 61 on Sunday to win the Bridgestone Invitational by five strokes for a second World Golf Championships win.
The world number three from Japan marched to the title with an eagle and seven birdies. His 16-under total of 264 put him five in front of two-time major winner Zach Johnson, who closed with a 68 for 269.
Matsuyama, the first player from Asia to win one of golf’s elite WGC titles, added the Bridgestone trophy to the HSBC Champions crown he claimed in October.
The dominant performance came in the final tune-up event for golf’s best before the last major of the season, the PGA Championship next week at Quail Hollow in North Carolina.
Matsuyama kick-started his round with an eagle at Firestone Country Club’s par-five second, where he chipped in from just off the green.
He capped his round with birdies at 16, 17 and 18 to join Jose Maria Olazabal, Tiger Woods and Sergio Garcia as the only players to shoot 61 on Firestone’s South Course.
“In fact, I played with Tiger four years ago when he shot 61, so I knew 61 was the number today,” Matsuyama said. “I was thinking about that at 16 — I knew if I birdied 16, 17 and 18 I could get there.”
He did — rolling in a six-footer at the last — and will go into the PGA Championship a hot favorite to become the first Japanese man to win a major championship — although he noted that he’s never been particularly successful in the PGA Tour event at Quail Hollow.
“All I can do is my best,” Matsuyama said.
That was certainly good enough on Sunday — although Matsuyama said he had no expectation of such a round after his pre-round practice.
“You wouldn’t have believed how I warmed up this morning,” he said.
“I was not hitting it good on the range. I did hit some good shots, but I was nervous all the way around because I really wasn’t sure of my swing today.”
Nevertheless, his eagle and three birdies saw him leading when he made the turn.
American Charley Hoffman applied some pressure with five birdies his first 11 holes, but couldn’t maintain his consistency in a 66 that saw him settle for third place on 270.
Johnson, who shared the overnight lead with Belgian Thomas Pieters, had three birdies and a bogey in his two-under effort — but parred his way through the last seven holes as Matsuyama consolidated his lead.
Johnson, seeking his first win since the 2015 British Open, was encouraged by his game but said of Matsuyama: “Clearly, we all ran into a buzz saw today.”
Pieters’s one-over 71 was good enough for fourth place on 272.
Northern Ireland star Rory McIlroy carded a 60 to head a group on 273 that also included Scotland’s Russel Knox (68), England’s Paul Casey (67) and Canadian Adam Hadwin (69).
British Open champion Jordan Spieth, who will be pursuing a career Grand Slam at the PGA Championship, closed with a 68 that left him in a group sharing 13th on 276.
“My game improved each and every day, even though my score didn’t reflect it today so I’m really excited going into Quail Hollow,” Spieth said.