Kawhi Leonard scored a sensational 33 points to help San Antonio put down the Toronto 102-95, which allowed the Spurs to remain unbeaten at home.
With San Antonio clinging to an 88-84 lead, Leonard hit two contested jumpers and then sank four free throws to secure the win.
The victory means that San Antonio (64-13) have established a franchise record for wins in a season that was set in 2005-06 when the Spurs went 63-19. The Spurs have now defeated every team in the NBA this season.
The Spurs are 39-0 at the AT&T Centre this season and have passed the 1995-96 Chicago Bulls record for the longest home win streak to start a season.
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