“We are expecting a wet and windy day at Newlands and have elected to play Danny Cipriani ahead of George Ford to give us a left-foot kicking option,” explained coach Eddie Jones.
His inclusion in place of Ford is one of four changes – three enforced – from the team that lost the second Test and the series in Bloemfontein last weekend.
Loosehead prop Joe Marler replaces Mako Vunipola, who returned home last weekend for family reasons.
No8 Billy Vunipola, a brother of Mako, was ruled out of the Cape Town tour finale by injury, and Nathan Hughes comes in.
Danny Cipriani starts for England for first time since dinosaurs roamed the earth*— robert kitson (@robkitson) June 21, 2018
*Well, Nov 2008, anyway.
Illness forced at change at loose forward with Brad Shields sidelined and Chris Robshaw recalled just one week after being dropped for the first time by Australia-born Jones.
There are three chances to the bench with prop Alex Hepburn, lock Jonny Hill and loose forward Sam Simmonds promoted in a 6-2 forwards/backs split.
Jones said: “We will need to jump out of the blocks quickly again and make sure we maintain that pressure and make good decisions.
“I have been really impressed with the fortitude of the squad under Owen Farrell, who is a young captain, and with a number of young players who have really stuck to the task.
“We have had a really upbeat training week. We are up for the battle and are going to rip in on Saturday.
“I want another committed performance where it will be crucial to maintain our composure when the heat is on.”
While only pride is at stake after South Africa won 42-39 in Johannesburg and 23-12 in Bloemfontein, England are desperate to snap a five-Test losing streak.
Before touring South Africa, England lost Six Nations Championship matches against Scotland in Edinburgh, France in Paris and Ireland in London.
The dramatic loss for form came after Jones won 24 of his first 25 Tests since succeeding Stuart Lancaster when hosts England flopped at the 2015 Rugby World Cup.
England team to play South Africa in the third Test at Newlands, Cape Town, on Saturday June 23 (22:00 UAE Time):
E Daly (Wasps); J May (Leicester Tigers), H Slade (Exeter Chiefs), O Farrell (Saracens, capt), M Brown (Harlequins); D Cipriani (Wasps), B Youngs (Leicester Tigers); J Marler (Harlequins), J George (Saracens), K Sinckler (Harlequins), J Launchbury (Wasps), M Itoje (Saracens), C Robshaw (Harlequins), T Curry (Sale Sharks), N Hughes (Wasps)
Replacements: L Cowan-Dickie (Exeter Chiefs), A Hepburn (Exeter Chiefs), H Williams (Exeter Chiefs), J Hill (Exeter Chiefs), M Wilson (Newcastle Falcons), S Simmonds (Exeter Chiefs), B Spencer (Saracens), D Solomona (Sale Sharks).
There are two changes in the front row as prop Jack McGrath and hooker Sean Cronin come in, with Niall Scannell and Cian Healy dropping to the bench.
Ulster winger Jacob Stockdale returns to the starting line-up, after he was a shock omission from Melbourne, as do Leinster No8 Jack Conan and former Chiefs inside centre Bundee Aki, now at Connacht.
They replace injured trio Andrew Conway, Garry Ringrose and Dan Leavy.
Schmidt is also forced into three positional changes, with captain Peter O’Mahony moving to open-side flanker, CJ Stander shifting to blindside to accommodate Conan, and Robbie Henshaw starting at outside centre.
The Ireland squad visited @TadhgKennelly & the @sydneyswans today and had a bit of fun when Tadhg met Mícheál Ó Muircheartaigh (AKA Ireland physio Colm Fuller) Check it out on youtube https://t.co/lyfti5s7Z2— Irish Rugby (@IrishRugby) June 20, 2018
Stockdale, McGrath and Aki were in the team for the opening Test, but it will be a first start of the series for Cronin and Conan.
There were further changes among the Ireland reserves, with John Cooney and Joey Carbery replaced by Kieran Marmion and Ross Byrne – the only member of the Irish squad not to have been involved in a matchday squad on the tour so far.
Ireland Team v Australia, Allianz Stadium, Sydney, Saturday, June 23, 14:05 UAE time
The Wallabies face Ireland in the deciding game of their three-match series at the Allianz Stadium in Sydney on Saturday (14:00 UAE time).
Ahead of the game, we take a look at three key battles.
NICK PHIPPS V CONOR MURRAY
Will Genia, no doubt, is a significant loss for the Wallabies due to an arm injury picked up in the second test, but his understudy Phipps can be just as lively and influential if provided with the right ball.
Although he lacks the same class and composure as Genia, the Waratahs man is just as creative and has the same razor-like passing ability to get his back line moving.
In what is a pivotal deciding match to the series, Phipps will need to be at his best against a player of Murray’s calibre.
Regarded as the best scrum-half in the world, there are few weaknesses evident in the Irishman’s game with crisp passing, unselfish decision-making, accurate box kicking and brilliant vision at the centre of his broad skillset.
MARIKA KOROIBETE V JACOB STOCKDALE
Another humdinger of a duel.
The Fijian-born winger may not have enjoyed his finest night in a gold jersey last week, with Ireland scoring 13 points during his stint in the sinbin for an overeager tackle.
But the 25-year-old will be crucial to the wing battle this weekend with his pace, power and defensive strength all key to putting Michael Cheika’s side on the frontfoot.
It must be remembered that the former NRL star made 11 tackles in Brisbane, including a try-saving hit on Stockdale that, if scored, could have changed the dynamic of the game.
The Melbourne Rebels winger may have the edge in the physical and defensive battle, but Stockdale possesses the pace and finishing ability to put Ireland in command of any contest.
The 22-year-old, who has scored 11 tries in 10 matches, was one of Ireland’s leading lights during the Grand Slam triumph in March and will be key for the Men in Green as the bid to win their first series in the southern hemisphere since 1979.
ADAM COLEMAN V JAMES RYAN
The tough Tasmanian may have picked up a cheek injury early into the second half of the Melbourne test, but he looks fit, firing and ready for another duel with Ryan.
With nine tackles in the first 40 minutes, Coleman remains an instrumental presence at the heart of the Wallabies pack, with his strong carrying and passing all serious threats.
At 6’7, the line-out is his obvious key strength, but away from that he puts in a serious shift to get on the ball and put teammates in favourable attacking positions.
The Rebels lock may have more big game experience, but the Irishman has shown before that he is up for any challenge no matter how big the task is.
Although just 21, Ryan is one of the rising stars in the game and can tackle solidly, win his own ball and show serious willingness at the breakdown.
Standing at the same height as Coleman, the Leinster star can run around the field like a six-litre Maserati and has lost just once in 25 professional matches between club and country.