England still won the series 4-1 but Pakistan’s success denied them a first home 5-0 ODI clean sweep and ended their dream of an unbeaten season in 50-over cricket.
Pakistan collapsed to 77 for three chasing 303 before a fourth-wicket partnership of 163 between Shoaib Malik (77) and Sarfraz Ahmed (90) turned this match in the Welsh capital their way.
Imad Wasim, born in the nearby south Wales city of Swansea, hit the winning runs when he struck a four off all-rounder Chris Jordan with 10 balls to spare as Pakistan finished on 304 for six.