With Chelsea currently fourth and enduring a stuttering defence of their title, United will be looking for a result that will see them keep pace with Manchester City, who are five points clear at the top.
Here, Press Association Sport’s Will Dennis looks back at five classic encounters between the two sides.
One of the biggest winning margins in an FA Cup final, United thrashed Chelsea to secure Sir Alex Ferguson his first league and cup double in Manchester. Gavin Peacock struck the crossbar with a long-range volley, but that was as good as it got for the Blues on the day as United took over in the second half at Wembley. Two identical Eric Cantona penalties and a Mark Hughes goal gave United a 3-0 lead in the space of 10 minutes, before Brian McClair got a fourth late on as United claimed their eighth FA Cup.
A game featuring brilliant goals and a stunning second-half Chelsea comeback also saw United’s unbeaten home run extend to 32 matches. The game’s best goal was its first with Jimmy Floyd Hasselbaink volleying a stunner into the top corner from the edge of the box. Paul Scholes replied and Teddy Sheringham and David Beckham then scored within two minutes of each other but Tore Andre Flo got one back for Chelsea to make it 3-2 at half-time. Flo completed Chelsea’s comeback in the second half.
The game which secured Chelsea’s second Premier League title under Mourinho. William Gallas gave Chelsea an early lead against their closest challengers, then Joe Cole produced a mesmerising piece of skill to beat Rio Ferdinand and Mikael Silvestre before firing past Edwin van der Sar. Ricardo Carvalho got the third goal to spark the celebrations. It was not all good news – for England fans especially. Wayne Rooney broke his metatarsal bone following a challenge from Paulo Ferreira just weeks before the World Cup in Germany.
In one of the Premier League’s most memorable games, Chelsea rushed into a 3-0 lead early in the second half only to leave the game with just a point, following three Manchester United goals in 25 minutes. An own goal from Jonny Evans gave Chelsea the lead in the first half with Juan Mata and David Luiz adding two more just after half-time. Two Rooney penalties made Chelsea worry, before Javier Hernandez headed in the equaliser six minutes from time to complete United’s comeback.
United raced into a 2-0 lead inside 12 minutes through an own goal from Luiz and a goal from Robin van Persie. Chelsea pressed throughout the remainder of the first half with David De Gea at his best to deny Fernando Torres. Eventually Mata got one back for the Blues with a free-kick just on the edge of the box, with Ramires bringing Chelsea level early in the second half. The game then turned on two contentious red cards, given to Branislav Ivanovic and Torres. It was not the end of the controversy, however, as United got their lead back through Hernandez, who tapped in from close range while in an offside position.
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