Spurs go into the game unbeaten in the last five league games, but have not fared well against their fellow top-six members this campaign.
United could give a first league start to former Arsenal man Alexis Sanchez, and despite criticism of their style of play under Jose Mourinho they currently have the longest unbeaten run in the league at eight games.
Here are the other facts and stats ahead of the game.
- Tottenham’s defeat in the reverse fixture earlier this season was their 80th in league competition against Manchester United – 11 more defeats than versus any other opponent.
- Manchester United have only won more league games against Aston Villa (85) and Arsenal (82) than they have against Tottenham (80).
- Spurs have won two of their seven Premier League matches against Manchester United under Mauricio Pochettino (D1 L4), as many as they’d won across their previous 26 games against the Red Devils, spanning eight different managers (Glenn Hoddle, David Pleat, Jacques Santini, Martin Jol, Juande Ramos, Harry Redknapp, Andre Villas-Boas, Tim Sherwood).
- The Lilywhites have won their last two home league games against Manchester United – they last won three consecutively against the Red Devils back in September 1966.
- Manchester United have won each of their last six games at Wembley Stadium, scoring at least twice every time. They last lost at the venue in the 2011 Champions League final (1-3 vs Barcelona).
- Spurs have picked up just three points in their five games against Arsenal, Chelsea, Liverpool, Man City and Man Utd this season (W1 D0 L4), fewer than any other ‘big six’ side in these fixtures.
- No team are on a current longer unbeaten run in the Premier League than Manchester United (8).
- Mauricio Pochettino is unbeaten in his last three Premier League home games against Jose Mourinho (W2 D1), winning 5-3 against Chelsea in January 2015, and in this exact fixture in May last season.
- Alexis Sanchez could make his Premier League debut for Man Utd in this game; he scored in Arsenal’s 2-0 win against Spurs in November, and could become the third player to score against them for two different clubs in the same Premier League season after Eric Cantona in 1992-93 and Benito Carbone in 1999-00.
- Harry Kane has had a hand in four goals in his last four Premier League games against teams managed by Jose Mourinho (three goals, one assist).
- Kane is just one goal shy of his 100th in the Premier League – none of the previous 26 players to reach the milestone have done so in a match against Manchester United, though Alan Shearer’s 100th in the competition for Newcastle United specifically did come against the Red Devils.
- Anthony Martial has scored in three consecutive Premier League games for the first time – he’s only scored in one of his previous 10 top-flight games in London, netting twice against West Ham in May 2016.
