Fernandinho’s blistering left-footed shot put the visitors up 1-0 in the 27th. Luan floated a shot over Lanus goalkeeper Esteban Andrada in the 42nd to double the advantage and cap a Copa that saw him named the best player of the 2017 edition of the South American club competition.
Although Lanus had produced four second-half goals against River Plate in the return leg of the semi-finals, there would be no miracle comeback this time.
Jose Sand converted a penalty in the 72nd to pull back one goal, but the Argentine side were denied a first Copa Libertadores title.
Gremio added their third title to those they won in 1983 and 1995.
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