The Football Association of Wales announced the news on Tuesday, though no reason was given.
Dylan Levitt steps up from the Under-21 squad to replace the Juventus midfielder for the crucial Euro 2020 qualifying clash against Azerbaijan on September 6, with the Belarus game a friendly following three days later.
Ramsey missed Juventus’ season opener with Parma after a summer of recovering from the hamstring injury which prematurely ended his Arsenal career.
He did play 15 minutes of a pre-season friendly against Triestina, however, but his first-team debut remains pending.
Eighteen-year-old Levitt is a Manchester United academy player who was called up to train with the senior squad at the end of last season, with a call-up to Wales’ training camp in Portugal following.