Spurs took their qualification hopes to the final Group B game at the Camp Nou with a late 1-0 win over Inter Milan at Wembley, thanks to Christian Eriksen’s 80th-minute strike.
They are still outsiders to progress, however, and will have to produce one of the most famous nights in the club’s history if they want to do it, as they have go to group winners Barca in a fortnight needing to match the result of Inter, who play at home to PSV Eindhoven.
It would mark an impressive achievement if they were able to do it, as they looked dead and buried at the halfway stage of the group with just one point from their opening three games.
Pochettino said: “All is possible in football. We have big respect to Barcelona, they are one of the best teams in Europe, it will be a so tough. But we have belief and faith that we can win.
“We need to show again a good level to compete at our best and arrive in Barcelona and compete at our best. We need fresh legs, fresh mind and no injuries. We need to arrive that way in Barcelona.”
Barca are guaranteed to be group winners, having taken 13 points from their five games, meaning they might rest some players for the clash on December 11.
Pochettino, however, is not expecting to get any favours.
“I expect that they are going to play with all the best players, but I don’t know how they are going to prepare the side,” he added.
“We need to approach the game in the best way and believe that we can win.
“What Barcelona is going to do is not in our hands. In the Champions League no-one is going to give a present and not care about the result.”
Spurs were made to work hard to get the win as Inter did everything in their power to disrupt the game and frustrate their hosts.
They had dominated the game, hitting the woodwork through Harry Winks, but looked to be heading out of the competition until Eriksen slammed home 10 minutes from time.
“I think the performance was very good, we fully deserved the victory,” he added. “We scored at the end but we beat a very good team.
“Inter Milan showed a great level, a team that’s so difficult to beat.”
Inter, playing in the tournament for the first time since 2012, would have been through with a point but their fate is no longer in their own hands.
Head coach Luciano Spalletti still reckons they will get through to the knockout stages if they beat PSV.
“If we do what we need to do I think we will go through, it depends on us even if practically it doesn’t,” he said.
“As long as we do our job I think we will go through. It is about what we do.
“They have got some top, top class players at Barcelona, they haven’t lost at home in the last five years in the Champions League and they will want to keep that record.
“I am saying that we have to do what we need to do, we are playing PSV and we have to beat them. If we can win this game it will give us a great chance of going through.”
Lionel Messi scored the opener and then set up Gerard Pique for the second. Luuk De Jong got the consolation goal for the hosts.
We rate the Barcelona players based on their performance on the night.
BARCELONA PLAYER RATINGS
Marc-Andre ter Stegen 4/10: A shocker from the German, had his blushes saved by the frame of the goal.
Nelson Semedo 5: Found it hard to keep up with Steven Bergwijn, ineffective in attack.
Gerard Pique 7: Solid performance by the centre-back, bagged the confirmation goal.
Clement Lenglet 6: A decent performance by the Frenchman, made some crucial interceptions.
Jordi Alba 6: Was not as assertive in attack, constantly troubled by Hirving Lozano.
Sergio Busquets 4: Gave the ball away easily, was far from his magnificent self.
Ivan Rakitic 3: Should not have played the game with the injury and his performance verified this.
Arturo Vidal 7: A solid performance by the Chilean, had two of his shots saved on the line.
Philippe Coutinho 7: Created a lot of chances, was getting past the PSV players with ease.
Lionel Messi 9: Made the difference with a goal and assist. A 10/10 performance if judged on a normalised scale.
Ousmane Dembele 9: One of his best performances this season, can make a case for being the best player on the pitch.
Malcom N/A: Should have converted Dembele’s low cross, not much involved with the ball.
Denis Suarez N/A: Played for 10 minutes when Barcelona were defending the game, mostly uninvolved.
The Blaugrana midfield was absolutely awful but the frontline bailed them out and prevented what could have been an embarrassing defeat.
We take a look at some of the talking points from the game.
BARCELONA’S MIDFIELD DROPS A SHOCKER
Ivan Rakitic and Sergio Busquests had a horrendous first half, committing silly mistakes that could have led to goals. Luuk de Jong and Hirving Lozano were the star performers for the hosts, latching onto every mistake but lacking the prowess to finish off the chances.
Steven Bergwijn was a constant threat on the left and Nelson Semedo found it hard to keep up with the Dutchman. The trio could have combined to score two goals in the first half alone, had the woodwork not betrayed them.
Barcelona’s midfield was suffocated by PSV’s pressing and gave the ball away easily, on many occasions.
Marc-Andre ter Stegen was at his distributive worst and lost possession way too often. It’s only fair that the German writes a thank-you note to the frame of the goal for saving his blushes.
De Jong’s header kissed the crossbar and Pablo Rosario hit the wrong side of the post in the dying moments of the first half.
A lead at half-time could have completely changed the dynamics of the second half for PSV ad they were unlucky not to achieve this.
OUSMANE DEMBELE ASSERTS HIMSELF
Two words for Dembele’s performance against PSV – absolutely elegant. The visitors were on the back-foot throughout the first half despite seeing more of the ball. Dembele’s performance could be the one positive that Ernesto Valverde would pick from the first half.
The Frenchman was a constant threat that the likes of Angelino and Gaston Pereiro just could not deal with.
The 21-year-old was clever with his decisions on the field, for a change and could have bagged a couple more assists with the quality of his passes.
The ambipedal winger completed all four of the dribbles that he attempted, delivered three key passes and was dispossessed just once during the 78 minutes that he played.
The Frenchman grabbed an assist as he set up Lionel Messi in a crowded PSV box and could have scored a couple more himself.
The youngster might just have established himself as an undisputed starter with a performance like this.
GALLANT PSV PUSH BARCA TO THE EDGE
The hosts were all over the Spanish giants whenever they had the ball. For all of Barcelona’s meaningless possession, it was PSV who created clear-cut chances.
Lozano has been on Barcelona’s radar after his impressive performance in the World Cup and the Mexican did not work hard to hide his admiration for the club too.
With a performance like this, it’s safe to say that the 23-year-old has drawn some attention from his potential future employers. The Mexican created quite a few clear cut chances for Bergwijn to miss. Lozano had a couple of chances which he should have buried but the youngster can be proud of staging a spirited performance.
De Jong was PSV’s best player on the night and deserved the consolation goal. The Dutchman was always among the thick of things that transpired in the neutral third and was absolutely relentless with his pursuit for the winner.
The result was a tad bit unfair for the hosts but PSV can be proud of a spirited performance that pushed Barcelona to the edge.