Daniel Cormier will make the first defence of his UFC heavyweight title against Derrick Lewis on November 3 at Madison Square Garden.
Light-heavyweight champion Cormier defeated Stipe Miocic in July to add the heavyweight crown to his collection.
Cormier was expected to tackle Brock Lesnar next but has instead been matched with Lewis at UFC 230 in New York.
Lewis produced a stunning knockout of Alexander Volkov at UFC 229 at the weekend, stopping his Russian opponent within the final 20 seconds while almost certainly trailing on the scorecards.
