Which matches are you most looking forward to seeing on day seven and who do you think will progress to the last 16 from our picks?
NOVAK DJOKOVIC (SER) vs KYLE EDMUND (GBR)
DJOKOVIC vs EDMUND
The Serb got a walkover against Jiri Vesely before his match against Mikhail Youzhny lasted just 32 minutes before his opponent withdrew.
The Serb will be fresh for this encounter and Edmund is unlikely to stand a chance.
SPORT360 VERDICT: Djokovic in straights.
RAFAEL NADAL (ESP) vs LUCAS POUILLE (FRA)
Nadal looked in top shape during his win against Kuznetsov.
He is in the second week of the US Open for the first time in three years and will fancy his chances against Pouille who had to fight for five sets against Bautista Agut.
SPORT360 VERDICT: Nadal in straights.
PETRA KVITOVÁ (CZE) vs ANGELIQUE KERBER (GER)
Kerber was just too good for 17-year-old Cici Bellis as she registered a 6-1, 6-1 win.
Kvitova too enters the match on the back of a straight sets win.
Tough to take a pick but Kerber should take this one, just about.
SPORT360 VERDICT: Kerber in three.
MADISON KEYS (USA) vs CAROLINE WOZNIACKI (DEN)
Keys pulled off the greatest comeback win of her career as she beat Naomi Osaka despite being 5-1 down in the final set.
She will need to dig deep against Wozniacki, who is on a roll at Flushing Meadows.
SPORT360 VERDICT: Wozniacki in three.
JOHANNA KONTA (GBR) vs ANASTASIJA SEVASTOVA (LAT)
Konta must be feeling confident after her straight sets win over Bencic.
But her opponent Sevastova is having a stunning tournament, having beaten No. 3 seed Muguruza.
Expect the Latvian to win a tough fight.
SPORT360 VERDICT: Sevastova in three.
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